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Year : 2018  |  Volume : 8  |  Issue : 3  |  Page : 177-180

Immunoglobulin a myeloma in a newly diagnosed sickle cell disease patient

1 Department of Haematology, College of Medicine, University of Ibadan/University College Hospital, Ibadan, Nigeria
2 Department of Haematology, University College Hospital, Ibadan, Nigeria

Correspondence Address:
Dr. John Ayodele Olaniyi
Department of Haematology, PMB 5116, University College Hospital, Ibadan
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijabmr.IJABMR_107_17

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Several neoplasms including hematological malignancies occurring in very few patients with sickle cell syndromes have been reported in literature, particularly as survival among these patients and diagnostic accuracy have continued to improve. Multiple myeloma (MM) has rarely been reported in patients with hemoglobin (Hb) S + C. We report a 65-year-old retired banker who was recently diagnosed with HbS + C. This patient developed MM with markedly elevated erythrocyte sedimentation rate, mild anemia, 80% bone marrow plasmacytosis, and elevated serum immunoglobulin A level, while plain X-ray of the lumbosacral spine showed multilevel vertebral collapse.

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